Lyme disease panel (IgG and IgM)

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Borelioza - pakiet podstawowy (IgG i IgM)

Podmiot leczniczy, nr księgi RPWDL 000000229528
700 punktów pobrań krwi, badań diagnostycznych i konsultacji specjalistycznych
Badania i konsultacje realizujemy samodzielnie oraz przez podwykonawców
Wynik online, bez skierowania
Działamy od 2020 r., kontynuacja pierwszego w Polsce internetowego sklepu z badaniami (sklep.etermed.pl, od 2013)

Original price was: 116,00 zł.Current price is: 91,00 zł. Oszczędzasz 21%!

Najniższa cena z 30 dni przed obniżką: 116,00 zł

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The panel includes:

Lyme disease IgG
Lyme disease IgM

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Categories: Laboratory, Risk factor assessment packages

Opis produktu

Whereany sample collection centre listed in the basket

Results turnaround timeup to 2 working days

Samplevenous blood (serum)

Preparationfasting is not required; no earlier than 3–4 weeks after a tick bite

Why Borrelia antibodies are tested

This panel is the first stage of Lyme disease investigations: measuring IgM antibodies (which appear earlier, during active infection) and IgG antibodies (which appear later and persist for a long time) using ELISA or CLIA. These tests are sensitive but have low specificity: they cross-react with antibodies produced in other infections and autoimmune diseases. Diagnosis therefore involves two stages: a positive or equivocal result requires confirmation by Western blot (immunoblot), and the doctor makes the diagnosis based on symptoms, not the result alone.

When to consider this test

3–4 weeks or more after a tick bite if symptoms develop: an atypical red rash, fever, joint and muscle pain or tiredness,
recurrent or migratory pain and swelling in large joints (especially the knee) without injury,
facial nerve palsy, nerve root pain, numbness or meningitis (neuroborreliosis; the doctor extends investigations to include cerebrospinal fluid),
heart rhythm disturbances or atrioventricular block in a young person after spending time in woodland,
chronic skin changes on the limbs (atrophic dermatitis).

How to prepare

Fasting is not required. Wait at least 3–4 weeks after the bite; otherwise, the result will be negative despite infection.
If you have typical erythema migrans, see a doctor rather than attending a laboratory: treatment starts immediately.
Tell your doctor about immunosuppressive medicines, previous syphilis, glandular fever or autoimmune diseases: these may cause false-positive results.
Testing the tick for bacteria is not useful; a positive result in the tick does not mean the person is infected.

Understanding your result

Results are reported as negative, equivocal (borderline) or positive, usually with a numerical value in units specified by the test manufacturer.

IgM	IgG	What it usually means
negative	negative	no infection or testing performed too early; if symptoms are present, repeat after 2–4 weeks
positive or equivocal	negative	possible early infection, but IgM is often falsely positive; confirm with IgM Western blot; after 3 months from symptom onset, IgM alone is not a basis for diagnosis
negative	positive	longer-standing or previous infection; confirm with IgG Western blot and assess symptoms
positive	positive	active or recent infection; Western blot confirmation and medical consultation

IgG antibodies may persist for years after successful treatment, so they are not used to confirm recovery. Diagnosing Lyme disease requires clinical symptoms plus two positive tests (ELISA and Western blot).

Other tests to consider

After a positive or equivocal result: IgG and IgM Western blot. For joint pain, the doctor also requests CRP, ESR, full blood count, rheumatoid factor; after a tick bite in endemic areas, also tick-borne encephalitis antibodies. Read more: Badania-Medyczne.pl.

Frequently asked questions

When should I have a Lyme disease test after a tick bite?

No earlier than 3–4 weeks after the bite. IgM antibodies appear after 2–4 weeks, and IgG after 4–6. Testing immediately after removing the tick gives a false-negative result and is not useful.

I have a red rash after a tick bite. Should I have a test?

No. Typical erythema migrans (an expanding patch larger than 5 cm, often with central clearing, appearing after a few days to a few weeks) is a basis for immediate antibiotic treatment without testing; antibodies are usually not yet present at this stage.

My result is positive. Do I have Lyme disease?

This is not yet certain. ELISA is the first stage; a positive or equivocal result must be confirmed by Western blot. IgG may remain positive for years after a previous, successfully treated infection, and IgM can be falsely positive.

Sources: ALAB laboratoria, Lyme disease IgG and IgM screening panel (3–4-week window, two-stage testing, erythema migrans without testing, cross-reactions); Chmielewski T., Strengths and limitations of serological diagnosis of infectious diseases, part 5: Lyme disease, Medycyna Praktyczna 2019 (ELISA + Western blot, IgM not useful after 3 months, tick testing not informative). For information only; does not replace medical advice.