{"id":67436,"date":"2015-03-18T08:00:00","date_gmt":"2015-03-18T07:00:00","guid":{"rendered":"https:\/\/badamysie.pl\/?post_type=product&#038;p=67436"},"modified":"2026-10-20T22:30:32","modified_gmt":"2026-10-20T20:30:32","slug":"vitamin-b6-laboratory-test","status":"publish","type":"product","link":"https:\/\/badamysie.pl\/en\/produkt\/vitamin-b6-laboratory-test\/","title":{"rendered":"Vitamin B6 &#8211; laboratory test"},"content":{"rendered":"<div class=\"bm-kv\">\n<div><b>Where<\/b>any blood collection point listed in the basket<\/div>\n<div><b>Results turnaround time<\/b>as specified by the laboratory (specialist test)<\/div>\n<div><b>Sample<\/b>venous blood (plasma), sample protected from light<\/div>\n<div><b>Preparation<\/b>fast for 12 hours; no B6 supplements or multivitamins for 24 hours<\/div>\n<\/div>\n<h2>Why vitamin B6 is tested<\/h2>\n<p>The test measures pyridoxal phosphate (PLP), the active form of vitamin B6, which is a cofactor in more than 140 enzymatic reactions: amino acid metabolism, synthesis of haem and neurotransmitters (serotonin, dopamine, GABA), and homocysteine metabolism. Deficiency is rare with a normal diet, but occurs in people with kidney disease, alcoholism, malabsorption syndromes and those taking certain medicines. Excess intake from supplements, which damages peripheral nerves, is now a more common problem.<\/p>\n<h2>When to consider this test<\/h2>\n<ul>\n<li>numbness and tingling in the hands and feet, and balance problems in someone taking B6 supplements (suspected excess),<\/li>\n<li>seborrhoeic dermatitis, cracks at the corners of the mouth, inflammation of the tongue, irritability, depression, microcytic anaemia with normal iron levels (suspected deficiency),<\/li>\n<li>raised homocysteine despite normal B12 and folic acid levels,<\/li>\n<li>treatment with isoniazid, penicillamine, hydralazine or levodopa, long-term use of oral contraception,<\/li>\n<li>chronic kidney disease, dialysis, alcoholism, coeliac disease, Crohn&#8217;s disease, following bariatric surgery,<\/li>\n<li>treatment-resistant seizures in infants (pyridoxine-dependent epilepsy), at a neurologist&#8217;s request.<\/li>\n<\/ul>\n<h2>How to prepare<\/h2>\n<ul>\n<li>Fast for 12 hours; drink only water in the morning. Have the sample collected in the morning.<\/li>\n<li>Do not take vitamin supplements, including B-complex and multivitamins, for 24 hours before sample collection. A doctor will decide whether a longer break is needed if the aim is to assess stores without supplementation.<\/li>\n<li>Bring a list of your medicines; some of them lower PLP.<\/li>\n<li>The test is performed at selected laboratories; check collection point availability when ordering.<\/li>\n<\/ul>\n<h2>How to interpret your result<\/h2>\n<p>The result is reported in \u00b5g\/l or nmol\/l (1 \u00b5g\/l PLP = 4,05 nmol\/l). The range depends on the method; as a guide, Mayo Clinic Laboratories gives 5\u201350 \u00b5g\/l for people who have fasted and are not taking supplements.<\/p>\n<table>\n<tr>\n<th>PLP<\/th>\n<th>What it usually means<\/th>\n<\/tr>\n<tr>\n<td>below the range<\/td>\n<td>deficiency; the doctor investigates the cause (diet, medicines, absorption, kidneys) and starts supplementation<\/td>\n<\/tr>\n<tr>\n<td>within the range<\/td>\n<td>adequate vitamin B6 status<\/td>\n<\/tr>\n<tr>\n<td>moderately above the range<\/td>\n<td>most often supplementation or a meal before the test<\/td>\n<\/tr>\n<tr>\n<td>significantly above the range (above 100 \u00b5g\/l according to Mayo)<\/td>\n<td>high-dose supplementation; stop supplementation if neurological symptoms are present; rarely, hypophosphatasia (the doctor then checks alkaline phosphatase)<\/td>\n<\/tr>\n<\/table>\n<p>Symptoms of neuropathy alongside a high result and supplement use are an indication to stop taking B6 products immediately, including those marketed for \u201cstress relief\u201d and \u201cimmune support\u201d, which often contain several tens of milligrams.<\/p>\n<h2>What to test alongside vitamin B6<\/h2>\n<p>For neuropathy: <a href=\"https:\/\/badamysie.pl\/en\/produkt\/vitamin-b12-laboratory-test\/\">vitamin B12<\/a>, <a href=\"https:\/\/badamysie.pl\/en\/produkt\/glucose-laboratory-test\/\">glucose<\/a>, <a href=\"https:\/\/badamysie.pl\/en\/produkt\/thyroid-stimulating-hormone-tsh-laboratory-test\/\">TSH<\/a>; for anaemia: <a href=\"https:\/\/badamysie.pl\/en\/produkt\/full-blood-count-laboratory-test\/\">full blood count<\/a>, <a href=\"https:\/\/badamysie.pl\/en\/produkt\/ferritin-laboratory-test\/\">ferritin<\/a>, <a href=\"https:\/\/badamysie.pl\/en\/produkt\/folic-acid-laboratory-test\/\">folic acid<\/a>; for raised <a href=\"https:\/\/badamysie.pl\/en\/produkt\/homocysteine-laboratory-test\/\">homocysteine<\/a>, the full set of B vitamins. Read more: <a href=\"https:\/\/www.badania-medyczne.pl\/?s=witamina+B6\">Badania-Medyczne.pl<\/a>.<\/p>\n<div class=\"bm-faq\">\n<h2>Frequently asked questions<\/h2>\n<details>\n<summary>Do I need to fast for a vitamin B6 test?<\/summary>\n<p>Yes, do not eat for 12 hours (water is allowed). Do not take vitamin B6 supplements or multivitamins for 24 hours before sample collection; they raise the result.<\/p>\n<\/details>\n<details>\n<summary>Is too much vitamin B6 harmful?<\/summary>\n<p>Yes. Long-term use of high doses (usually above 100\u2013200 mg daily, sometimes less) causes sensory neuropathy: numbness, tingling and pain in the feet and hands, and balance problems. Symptoms usually improve after stopping supplementation, but do not always resolve completely.<\/p>\n<\/details>\n<details>\n<summary>Why is this test expensive and why does it take longer?<\/summary>\n<p>The active form of the vitamin (pyridoxal phosphate) is measured using HPLC at a small number of laboratories, and the sample must be protected from light and frozen. This accounts for the higher price and longer turnaround time compared with routine tests.<\/p>\n<\/details>\n<\/div>\n<p class=\"bm-src\">Sources: <a href=\"https:\/\/www.alab.pl\/badanie\/witamina-b6-2\" rel=\"noopener\">ALAB laboratoria, Vitamin B6 test (HPLC method, PLP, symptoms of deficiency and excess, limited availability)<\/a>; <a href=\"https:\/\/www.mayocliniclabs.com\/test-catalog\/overview\/42360\" rel=\"noopener\">Mayo Clinic Laboratories, Vitamin B6, Plasma (PLP range 5\u201350 \u00b5g\/l, fasting for 12 h, no supplements for 24 h, protection from light, interpretation of high values)<\/a>. This information does not replace a medical consultation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A blood test to measure vitamin B6 levels. It is used in the diagnosis and treatment of vitamin B6 deficiency.<\/p>\n","protected":false},"featured_media":39086,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[2230],"product_tag":[],"class_list":["post-67436","product","type-product","status-publish","has-post-thumbnail","product_cat-other-laboratory-tests","first","instock","virtual","sold-individually","taxable","purchasable","product-type-simple"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.4 - aioseo.com -->\n\t<meta name=\"description\" content=\"Vitamin B6 test for deficiency. No referral. Buy online: over 700 points in Poland. Results online. 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