{"id":63889,"date":"2014-04-28T22:58:40","date_gmt":"2014-04-28T20:58:40","guid":{"rendered":"https:\/\/badamysie.pl\/produkt\/vitamin-b12-laboratory-test\/"},"modified":"2026-10-10T22:42:08","modified_gmt":"2026-10-10T20:42:08","slug":"vitamin-b12-laboratory-test","status":"publish","type":"product","link":"https:\/\/badamysie.pl\/en\/produkt\/vitamin-b12-laboratory-test\/","title":{"rendered":"Vitamin B12 &#8211; laboratory test"},"content":{"rendered":"<div class=\"bm-kv\">\n<div><b>Where<\/b>any sample collection centre listed in the basket<\/div>\n<div><b>Results turnaround time<\/b>up to 2 working days<\/div>\n<div><b>Sample<\/b>venous blood (serum)<\/div>\n<div><b>Preparation<\/b>in the morning, after fasting for 8\u201312 hours; no B12 supplements (agree this with your doctor)<\/div>\n<\/div>\n<h2>Why vitamin B12 is tested<\/h2>\n<p>Vitamin B12 (cobalamin) is essential for red blood cell production, DNA synthesis and the formation of nerve sheaths. Deficiency develops slowly because liver stores last for years, but once depleted, it causes megaloblastic anaemia and nerve damage: numbness, balance problems, memory difficulties and low mood. Neurological symptoms can occur without anaemia and may be partly irreversible, so it is advisable not to wait for an abnormal full blood count.<\/p>\n<h2>When to consider this test<\/h2>\n<ul>\n<li>a vegetarian or vegan diet (B12 is found only in animal products and fortified foods),<\/li>\n<li>anaemia, especially with large red blood cells (raised MCV), or an abnormal full blood count,<\/li>\n<li>numbness and tingling in the hands and feet, impaired sensation and balance, worsening memory or depression,<\/li>\n<li>long-term treatment with metformin or heartburn medicines (proton pump inhibitors), stomach and intestinal disorders (coeliac disease, Crohn&#8217;s disease, SIBO, or following bariatric surgery),<\/li>\n<li>age over 50, alcohol misuse, pregnancy or breastfeeding,<\/li>\n<li>monitoring treatment for deficiency.<\/li>\n<\/ul>\n<h2>How to prepare<\/h2>\n<ul>\n<li>Fast for 8\u201312 hours, drinking only water in the morning. Have the sample collected in the morning.<\/li>\n<li>Avoid testing within 2 weeks of a B12 injection. Oral supplements raise the result; discuss whether to stop them with your doctor.<\/li>\n<li>Tell your doctor about metformin, heartburn medicines, contraception and alcohol consumption. Stop high-dose biotin for one day before sample collection.<\/li>\n<\/ul>\n<h2>Understanding your result<\/h2>\n<p>Results are reported in pg\/ml (equivalent to ng\/l) or pmol\/l (1 pg\/ml = 0,738 pmol\/l). Laboratory reference ranges are broad (Mayo: 180\u2013914 ng\/l), but clinical decision thresholds are important in practice:<\/p>\n<table>\n<tr>\n<th>Vitamin B12<\/th>\n<th>What it usually means<\/th>\n<\/tr>\n<tr>\n<td>below 200 pg\/ml<\/td>\n<td>clear deficiency; usually already accompanied by anaemia or neurological symptoms, requiring treatment<\/td>\n<\/tr>\n<tr>\n<td>200\u2013400 pg\/ml<\/td>\n<td>borderline range; deficiency is possible despite a \u201cnormal\u201d result; the doctor also requests methylmalonic acid (MMA), holotranscobalamin or homocysteine<\/td>\n<\/tr>\n<tr>\n<td>above 400 pg\/ml<\/td>\n<td>adequate vitamin B12 status<\/td>\n<\/tr>\n<tr>\n<td>well above the reference range without supplementation<\/td>\n<td>requires assessment: liver disease, kidney disease or myeloproliferative disorders<\/td>\n<\/tr>\n<\/table>\n<p>Investigating anaemia requires B12 and folate to be measured together, as folate treatment alone masks B12 deficiency and allows nerve damage to progress.<\/p>\n<h2>Other tests to consider alongside vitamin B12<\/h2>\n<p>Usually: <a href=\"\/en\/?s=morfologia&amp;post_type=product\">full blood count<\/a>, <a href=\"\/en\/?s=kwas+foliowy&amp;post_type=product\">folate<\/a>, <a href=\"\/en\/?s=ferrytyna&amp;post_type=product\">ferritin<\/a>; for a borderline result, <a href=\"\/en\/?s=homocysteina&amp;post_type=product\">homocysteine<\/a> or <a href=\"\/en\/?s=kwas+metylomalonowy&amp;post_type=product\">methylmalonic acid<\/a>; if an autoimmune cause is suspected, <a href=\"\/en\/?s=przeciwcia\u0142a+przeciw+kom\u00f3rkom+ok\u0142adzinowym&amp;post_type=product\">parietal cell antibodies<\/a> and intrinsic factor antibodies. Symptoms and diet: <a href=\"https:\/\/www.badania-medyczne.pl\/?s=witamina+B12\">Badania-Medyczne.pl<\/a>.<\/p>\n<div class=\"bm-faq\">\n<h2>Frequently asked questions<\/h2>\n<details>\n<summary>Do I need to fast for a vitamin B12 test?<\/summary>\n<p>Yes, do not eat for 8\u201312 hours and drink only water in the morning. ALAB recommends morning sample collection.<\/p>\n<\/details>\n<details>\n<summary>My result is 250 pg\/ml. Does this indicate deficiency?<\/summary>\n<p>This is within the borderline range. Values of 200\u2013400 pg\/ml (150\u2013400 ng\/l according to Mayo) do not exclude deficiency at the cellular level; the doctor also requests methylmalonic acid or holotranscobalamin, sometimes homocysteine.<\/p>\n<\/details>\n<details>\n<summary>Can supplements distort the result?<\/summary>\n<p>Yes. B12 tablets, and especially injections, raise the result for weeks. Wait at least 2 weeks after an injection; stop oral supplements only after agreeing this with your doctor.<\/p>\n<\/details>\n<\/div>\n<p class=\"bm-src\">Sources: <a href=\"https:\/\/www.alab.pl\/badanie\/witamina-b12-o83\" rel=\"noopener\">ALAB laboratoria, Vitamin B12 (preparation, thresholds of 200\/400 pg\/ml, indications)<\/a>; <a href=\"https:\/\/www.mayocliniclabs.com\/test-catalog\/overview\/9154\" rel=\"noopener\">Mayo Clinic Laboratories, Vitamin B12 Assay, Serum (reference range 180\u2013914 ng\/l, borderline range 150\u2013400 ng\/l, MMA, B12 injections)<\/a>. For information only; does not replace medical advice.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A blood test to measure vitamin B12 levels. Used to diagnose and manage vitamin B12 deficiency, and to investigate and manage anaemia or neurological disorders.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"featured_media":63891,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[2230],"product_tag":[],"class_list":["post-63889","product","type-product","status-publish","has-post-thumbnail","product_cat-other-laboratory-tests","first","instock","sale","virtual","sold-individually","taxable","purchasable","product-type-simple"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"Measure vitamin B12 to investigate deficiency, anaemia and neurological symptoms. 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